01✓
Unique in Region
The sole team validated with dual original Cell methods on large retrospective patient cohorts.
✦ Arc·ell · Single-Cell Tumour Evolution Platform
See cancer
evolve, cell by cell
Pioneering Arc-well and wellDR-seq to link archival tissue, clonal phylogenies, and same-cell DNA+RNA states into scalable solutions.
2
Original Cell Papers
73,976
Clinical Single Cells
DNA+RNA
Same-Cell Co-Assay
TECHNOLOGY CONTINUUMFrom Sample to Mechanism, to Product
01
↓Archival FFPEBring retrospective cohorts into single-cell studies
02
↓Arc-wellSingle-cell DNA · CNA · Clonal Phylogeny
03
wellDR-seqSame-cell DNA+RNA · Functional Mechanism
CORE KITS
ARCELL One
DATA SUITE
CORE TECHNOLOGY
Two Original Cell Methods,
Two Critical Bottlenecks Solved
Arc-well uncovers where clones originate; wellDR-seq reveals why distinct clones drive therapy resistance.
Cell 2023Arc-well
Unlock Archival FFPE for Single-Cell DNA Sequencing
High-throughput single-cell genomics directly identifies copy number alterations (CNAs) from archival tissues, resolving clonal trees in clinical cohorts.
27 Cohorts · 40,330 Single Cells · Up to 31-Yr Archives
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Cell 2025wellDR-seqLink DNA Clones & RNA States within the Same Cell
Simultaneously profiles genome-wide CNAs and 3' transcriptomes from single cells, bridging clonal ancestry with active functional phenotypes.
12 ER+ Breast Cancers · 33,646 Single Cells
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Direct Clonal Quantification|Same-Cell DNA + RNA|Clinical Sample Compatibility
TECHNOLOGY ADVANTAGE
Two Breakthroughs in Cell,
Forming Defensible Global Barriers
02✓
Global Frontier
High-throughput same-cell DNA+RNA directly pairs whole-genome CNAs with transcriptomes without computational inferences.
03✓
Challenging Samples
Unlocks decades-old FFPE pathology banks into high-resolution single-cell genomic data assets.
04✓
Product Ready
Full translation pipeline across sample prep, nanowell chips, chemistry kits, and automated analytical software.
* Supported by original peer-reviewed Cell publications and clinical cohort validations.
CONCEPT PROTOTYPE · FUTURE PRODUCT
PRODUCT VISION
ARCELL One
Single-Cell System
Standardised workflows from sample preparation and nanowell isolation to library construction and automated analytics.
PREPSample Prep & QC
WELLDispense · Image · Select
LIBRARYDNA · DNA+RNA Chemistry
ANALYSISCNA · Clonal Phylogeny
ARCELL One represents a research-use-only (RUO) conceptual roadmap.
PRODUCTIZATION
From Service Validation to Industrial Scale
Validating cohorts via research services, standardizing core kits, and scaling via automated workstations.
Research Services
Establish solid tumor cohorts and publication-grade insights.
Core Kits
Standardize SOPs, library chemistries, and proprietary consumables.
ARCELL One
Automated workstations for high-throughput discovery and translation.
CORE LEADERSHIP
Synergy of Academic Invention & Industrial Execution
Coupling continuous method invention with translational bioinformatics and disciplined execution.
CHIEF SCIENTIST
Kaile Wang, Ph.D.
Principal Investigator ｜ Professor ｜ Ph.D. Supervisor
Pioneering high-throughput single-cell technology and clonal evolution; inventor of Arc-well, wellDR-seq, and SNuBar.
GENERAL MANAGER
Jing Li
Head of Industrial Platform ｜ Precision Medicine Translation
Extensive leadership in bioinformatics, automated analytics, commercial delivery, and precision oncology translation.
Build Sustainable Clonal Evolution Cohorts
Supporting archival FFPE tissue and fresh solid tumors with a 6–8 week pilot validation.